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A variety of big cat, panthers are found in the Thousand Needles, Swamp of Sorrows, and all over Stranglethorn Vale. Since the Cataclysm, they have disappeared from the Swamp of Sorrows.
A being like a "winged panther" was one of the Ancients that fought during the War of the Ancients. It had almost human hands. (Sund 210)